Monday, December 24, 2012

Master hypertension and use medicine in an all-round way

Master hypertension and use medicine in an all-round way
The hypertension situation of our country is severe day by day, nearly there are 200 million hypertension patients in the whole country, the ill rate of hypertension is up to 18.8%. But only 6.1% of control rate of hypertension of our country, most patients' blood pressure has not been controlled, hypertension has already become one of our country's serious public health problems.
Blood pressure is different to some extent too in 24 hours, depressor " 3 times of one day " It is unreasonable to take
Discover, the human body is under the function of the biological clock, blood pressure is different to some extent too in 24 hours. Usually blood pressure rises continuously after awakening early morning, 8 of morning reaches the highest peak to 10 o'clock, drop gradually subsequently, 3 of afternoon slightly fluctuates to 6 o'clock. People are after falling asleep, the organism is in having a rest state mostly, metabolism slows down, blood pressure drops correspondingly too. Blood pressure most low from mid-night to awakening, blood flow, slowly, the brain organize the blood supply to be enough, some blood coagulation materials in the blood, such as blood platelet, fibrinogen,etc., also extremely apt to stick and attach to membrane in the blood vessel, gather into a clot, especially when the elderly have atherosclerosis, membrane coarse in the blood vessel, is apt to form embolus, block the intersection of brain and blood vessel take place brain block up, so brains blocks up and has illness coming on with early morning it is many. Therefore is easy to find out, take depressor unreasonably 3 times on a traditional day, and it is more dangerous to especially take depressor before sleeping at night.
Japanese scholar points out, the elderly's hypertension needs to use medicine in the daytime. Our country make clinical observation too, make propranolol (general to endure Lip river) Full-time dosage,in order to lasting medicining and on the early morning each observe curative effect medicine, as a result two kinds of methods step down the result is unanimous, it means the method of once of offering medicine in early morning of every day, can obtain good therapeutic effect, bad reaction such as dizzy, many dream, tired relatively rare. Another someone give hypertension patient, take flat the intersection of Buddhist nun and group, according to traditional the intersection of method and 1 day 3 one, one (10 milligrams) for once ,Round-the-clock every blood pressure of moment have, reduce finally, but 24-hour the intersection of cycle and rhythm its with basically identical when not taking medicine still at time phase. Another group takes test method, awaken in early morning, take once, give 2 slices of medicines (20 milligrams) ,Find the round-the-clock of blood pressure periodicity changes to some extent. Blood pressure is relatively steady after awakening in early morning, the ascendant trend can be controlled in daytime, but it is not obvious to drop at night. So can already control blood pressure effectively, has reduced serious complications such as cerebral hemorrhage,etc.,
Therefore, the essential hypertension patient takes medicine once in early morning, is superior to taking medicine 3 times for a traditional one day, and can lighten the burden of taking medicine many times, avoid leaking the clothes, it is easy to insist on for a long time.
Most experts maintain at present the time to take depressor is best in once of 8 points, once of 2 points of afternoon of morning. Unsuitable to take depressor before sleeping, even a severe hypertension patient, can only take 1/ 3 of the dosage in the daytime before sleeping. So can keep 24-hour blood pressure steady, prevent the occurrence of heart, blood vessel serious complication of brain.
The administration time of essential hypertension patient should also consult, step down medicine effective blood medicine density time and blood pressure fluctuation law on function. It is generally acknowledged that only needs to take long-efficiency depressor of once (such as the slice of pyridine of flat, compound reserpine ammonia benzene butterfly of chlorine of ammonia benzene sulfonic acid) every day Suitable for on morning take the 7th 6,need one that take 2 times not to be hit by result depressor (benzene lasted stretch gentlely, wine is sour to last Lip river beautifully in stone in for example nitre) every day Suitable for, 6 16 take to 7 o'clock and afternoon to 17 o'clock morning, medicine can until two blood pressure give play to curative effect effectively peak period in this way.
Everybody has one's own blood pressure biological clocks to regulate the law, it is not absolute to refuse to obey depressor before sleeping
Doctor or generally all recommending on the medical textbooks " Do not take depressor before sleeping " . This view is suitable for a general hypertension patient, especially the patient who takes fugitive depressor. To the hypertension patient or some special hypertension patients who take the medicine long-efficiencily and step down, do not " take depressor before sleeping " It is not absolute.
Long-efficiency depressor is a old hypertension patient more suitable depressurization medicine, 1 times a day, it is very extensive to employ at present. Maintain long-efficiency depressor take while being about in will it be 7 o'clock morning, can better to control blood pressure of daytime rise and prevent night apt the intersection of body posture and the intersection of and hypotension that take place generally. However, a lot of clinical cardiovascular disease experts think, can't may not also put long-efficiency depressor the clothes before sleeping. Especially appear blood pressure is raised for the essential hypertension patient of the characteristic before dawn, it can be more easy to control blood pressure fluctuation to take before sleeping. The function time of long-efficiency depressor is long, but get up the time of the result is slower. Take medicine at about 9 o'clock in the evening, reach the blood medicine peak after midnight, 4 still has a prominent depressurization effect to 6 o'clock before dawn. Hypertension gets effective control from the time when this can make in the morning.
For cerebrovascular diseases treat depressurization of patient,recommend expert let's employ angiotensin not to be lasted enzyme inhibitor and oh piperazines step down diuretic. This kind of patient's blood pressure autoregulation potentiality is obviously reduced, even the curve of blood pressure fluctuation disappears day and night. The blood flow is mainly regulated by the arterial pressure level in the cranium, namely pour into and press in the cranium with artery blood pressure fluctuation, so, take medicine in the morning or in the evening the relation is not big. Brief on in accordance with general the intersection of profit and foreign result of study that, take, cough incidence lower notably evening. But diuresis steps down it is good that medicine such as Yin reaches amine, a pair of hydrogen chlorothiazide of handkerchief etc. to take medicine in the morning, so can make evening go to toilet few.
Everybody's blood pressure has one's own blood pressure biological clocks to regulate the law, it is all " low on daytime high night " that it is stereotyped that not ,Preferably can carry on for 24 hours with the help of doctor dynamic blood pressure is monitored, find out one's own blood pressure change law, pair step down medicine clothes 2 hours before hypertension that the most comes about. Once confirm oneself as hypertension from the morning, will step down the medicine will be put after waking up before dawn and taken more scientifically; As to the patient with tall blood pressure at a few night, can adopt medicines long-efficiencily and step down to take before sleeping.
Some step down the intersection of medicine and dosage form require, must give medicine before going to bed evening, for example the intersection of Vera and the intersection of handkerchief and the intersection of rice and pulse that foreign countries develop release preparation, take before going to bed, the pulse release at next day before dawn about 4 o'clock, the medicine appears at the point of raised danger of blood pressure, have reflected the technological advantage that demanding and high technology of therapeutics releases regularly of division of day and night. For held in place with a net and like etc. aliving, has had large research already, indicate to treat function in time slot with taking medicine to have nothing to do, so long as take medicine regularly every day.
Hypertension patient's blood pressure level of the section in summer of winter differs, the amount of medicine taken should be adjusted
Much hypertension patients take, step down medicine assortment and dosage without changing throughout the year, how to eat summer, winter return how to eat. In fact, hypertension patient's blood pressure level of festival in the summer of winter is differentiated, use pharmaceutical of depressor
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