The hepatitis B patient is able to bear medicines and can find the early-warning signal
It is reported (special correspondent Ni LiDong) Subsidiary medical worker of infectious disease department of Rui Jin hospital of Shanghai Communications University medical college, have issued the latest research results regarding B-mode hepatitis virus' accurate kind of evolution and antiviral treatments are replied on studying the magazine " Gut " at international top intestines and stomach disease recently, the first system has explained the impact on accurate kind of evolution of hepatitis B and virus of antiviral treatment in the world. This research is submitted to big medical college for test dean Professor Zhang XinXin's guidance by Shanghai, doctoral candidate Liu Feng,etc. finishes.
According to the introduction of Zhang XinXin, difference between the the same kinds of genetic the intersection of type and virus call that " accurate kind " . Under the natural state, the gradual progress that accurate kind will change in the virus, this is accurate kind of evolution. Under the circumstances that the medicine is intervened, the accurate kind of evolution will be more complicated. Study the intersection of hepatitis B and the intersection of virus and accurate kinds of evolution, hope, find the intersection of hepatitis B and antiviral treatment, able to bear early warning signal of medicine.
Because chronic B-mode virus hepatitis have, radically treat method is antiviral to treat key yet at present. But is able to bear medicines and not reply patient's prognostic difference, develop and rise for the probability of liver cirrhosis and hepatocarcinoma. Predict the antiviral treatment replies and able to bear medicines and happens and can intervene the patient in early days in early days, thus improve the prognosis. This research uses molecule cloning and bioinformatics technology, evolving in the angle from the molecule canvasses the accurate evolution characteristic in early days of kind of hepatitis B and virus in different antiviral medicine treatment, it is obviously different to find differently and treat accurate kind of evolution modes of hepatitis B and virus which replies the patients, have, reply the intersection of hepatitis B and the intersection of virus and accurate kinds of evolution of patient than slow complicated. Hepatitis B the intersection of virus and accurate kind evolve in early days characteristic can predict antiviral long-term curative effect of treatment accurately.
The first system in the world of this research results has explained the impact on accurate kind of evolution of hepatitis B and virus of antiviral treatment, have announced the accurate kind of relations with long-term antiviral curative effect of hepatitis B and virus, and studied and opened up the new field in order to be able to bear the medicine mechanism. Achievement and new developing to check order this technology combine together, can early predicting, treating curative effect for a long time accurately, offer the decision basis to clinical individual against virus treatment.
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