Pay close attention to the fact children use medicines to be safe

Pay close attention to the fact children use medicines to be safe
A few days ago, come from the intersection of British and medicines and the intersection of health and the intersection of products and the intersection of children and the intersection of cold drug and result of study that administration bureau release initiate numerous report of media first, some medias have used especially " 69 kinds of cold drugs contain the poisonous composition " , " cold drug is fatal and dangerous " , " cold drug does not cure the disease to hurt one's feeling instead " Wait for the title. To the public doubt and anxious, recently, at the forum organized by Chinese nonprescription drug association, some authoritative pharmacy experts, pediatrics experts, respiratory medicine experts in our country are right " Whether the child can use cold drug " Go on and discuss, and therefore has initiated expert's safe discussion to children's administration in question.
Children's cold is excessive in treatment
"It is excessive to the treatment of children's cold at present, often antibacterial, antiviral medicine which relieve symptom is used completely. This is a important reason for serious bad incident too. " The intersection of Peking University and the People's Hospital breathe the intersection of head of the department and Cao, take dragon Professor and say, this " has a reason of the doctor, also there is reason of children parents " .
Cao says according to the dragon, in the face of ordinary cold patients of children, if the doctor advices" comes back home to have a rest, drink more water " And not if writing a prescription, children parents will not agree. Meanwhile, ordinary cold can cause other complications, the doctor have to write a prescription too, otherwise once the serious consequence takes place, will have to bear responsibility.
It says, cold drug is the same as antibiotic that the third hospital in Peking University breathes professor of internal medicine Yao WanZhen, have already become one of the medicines easiest to abuse.
Medicines Du WenMin, deputy managing director of monitoring center of bad reaction in Shanghai say, it is more serious to reuse the phenomenon containing the same kind of composition cold drug clinically.
Professor of Shanghai children's hospital Lu Quan says, it is still necessary for children to use cold drug to treat to the ill, but must avoid misapplying, misusing, using medicine excessively and repeatedly. For example, 3 children that Britain announces are due to for taking the death of cold drug reasons, find the enormous exceeding amount of alkali of false Chinese ephedra, the reason is a medicine to reuse the same component.
Use issue of cold drug rationally children, Ministry of Public Health the whole country use medicine rationally the intersection of monitoring net and the intersection of expert panel and member, grandson, expert of pharmacy, say faithfully, it is not a cause of disease which treats cold to resist cold drug, but treat symptom. Resist symptom that cold drug can relieve cold, but can't dispel cold, even can't shorten the time of cold.
The grandson introduces faithfully, the data from Center for Disease Prevention and Control of U.S.A. reveal, in 2004 and 2005, 1519 children under the age of 2 presented bad reactions such as fainting from fear, cardiovascular, breathing, nervous system,etc. after using cold drug in U.S.A..
Grandson's faithful suggestion, adopt drinking the water to child's cold more, takes more time to rest and some other physical methods, physics temperature-dropping, develop nose, pay attention to the intersection of person who ventilate and method, can play a role in relieving symptom too.
The grandson says faithfully, synthesize the security information regarding children used cold drug released in the world, the use of children cold drug should follow the following principles: The infant and pre-school children under the age of 2 forbid; Use until child 12 years old is careful at 6 years old; Being in 12 can rest assuredded use,provided that can't dosage, courses of treatment ultra ultra at will. The non-prescription that our country is used for solving heat to ease pain resists cold drug, has stipulated clearly that being used for solving hotly can't exceed 3 days, stopping the pain can't exceed 5 days, it is safe to most patients.
According to " adult narrowing it " It is not scientific to give the administration to children
Du WenMin says, did not do clinical experiment to the cold drug that children used in the past, the dosage of children's administration is only a rough one, " In principle " Estimation,for pair for " the adult when regard as and dwindle children " To confirm dosage. That need is to strengthen management now, but not can't use cold drug.
The grandson explains faithfully, in view of the safe reason, the development of child's clinical pharmacology is with employing receiving the great restriction, can not be chosen the healthy volunteer, classical method,etc. that can't adopt placeboes and contrast either. So, clinical 80% in the manual of the medicine used have not recorded child's amount of medicine used. " child is not the adult narrowing it " ,According to " adult narrowing it " To calculate children's amount of medicine used is non- scientific.
Lu Quan says even, the security norm of children's administration needs strengthening. He says, while writing 2005 edition pharmacopoeias, he is responsible for writing the pediatrics part in the notice of clinical application. But because of the deficiency of the clinical test data, " children's determination of using medicine quantity is very difficult " .
Cao talks for example according to the dragon, administration of a child doing the clinical trial, enlarges the dosage by 5 times to use for adults, after testing the security, and then use for children according to the original dosage. Because it is very difficult that children do the clinical trial in administration, clinical ethics in the know agrees not to pass either. The ability to receive these data by oneself of our country is relatively weak, but should consult more WHO and foreign datas.
Expert say medicines might not undergo the experimental study of pediatrics merchandize, (research and clinical research before being clinical) ,Or the ultra indication of medicines is used in children, these cause children to use medicine quantity to be indeterminate, cause the bad reaction even die, or it is insufficient to lead to the fact to medicine quantity, cause and fail to respond to any medical treatment, or is not suitable for children's dosage form or for the medicine route, it is unable to be used in children,etc. and some has medicines curing advantage.
It is reported, in order to solve these problems fundamentally, European Union stipulates, since July 26, 2008, must file pediatrics and study the plan while applying for new medicine; Since January 26 of 2009, apply to file pediatrics and study the plan too in new indication. Pediatrics study, plan, research and develop the procedure by medicines gone on for guaranteeing to produce the essential data to mean, and these data determine whether this medicines will be sanctioned using for children.
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